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How Laboratory Analyzers Connect with a Laboratory Information System (LIS) to Streamline Laboratory Workflows

How Laboratory Analyzers Connect with a Laboratory Information System (LIS) to Streamline Laboratory Workflows

Levy Muguro
Written by Levy MuguroICT Officer
2 min read·Aug 17, 2026

Modern medical laboratories process hundreds or even thousands of patient samples every day. Managing this workload manually is not only time-consuming but also increases the risk of transcription errors, delayed reporting, and reduced productivity.

This is where the integration between laboratory analyzers and a Laboratory Information System (LIS) becomes essential. By allowing analyzers and the LIS to communicate automatically, laboratories can eliminate repetitive manual tasks, improve accuracy, and deliver test results to clinicians much faster.

What is a Laboratory Information System (LIS)?

A Laboratory Information System (LIS) is software designed to manage laboratory operations from patient registration and sample tracking to test result reporting and quality control. It serves as the central hub that coordinates laboratory activities and ensures that patient information and test results are securely managed.

How Do Laboratory Analyzers Connect to an LIS?

Modern laboratory analyzers communicate with an LIS using standardized communication protocols. The most common methods include:

  • ASTM (American Society for Testing and Materials): A widely adopted protocol that allows laboratory instruments to exchange work orders and test results with an LIS.
  • HL7 (Health Level Seven): A healthcare messaging standard commonly used when integrating the LIS with hospital information systems and electronic medical records.
  • TCP/IP over Ethernet: Most modern analyzers communicate through a local network, enabling fast and reliable data exchange.
  • Serial Communication (RS-232): Many older analyzers still use serial ports for communication with middle-ware or directly with an LIS.

Typical Workflow

  1. A patient is registered in the LIS.
  2. A laboratory request is created and a bar-code is printed.
  3. The sample is collected and labeled with the bar-code.
  4. The analyzer scans the bar-code and requests the corresponding test order from the LIS.
  5. The analyzer performs the requested tests automatically.
  6. Once testing is complete, the analyzer sends the results back to the LIS.
  7. The LIS validates, stores, and presents the results for review before generating the final laboratory report.

Benefits of Analyzer-LIS Integration

  • Eliminates manual entry of test results.
  • Reduces transcription errors.
  • Speeds up turnaround time.
  • Improves sample traceability through bar-code identification.
  • Enables real-time result reporting.
  • Supports quality assurance and audit trails.
  • Increases laboratory efficiency and staff productivity.
  • Allows laboratory personnel to focus on quality control and patient care instead of repetitive administrative tasks.

Conclusion

The integration of laboratory analyzers with a Laboratory Information System has transformed modern laboratory operations. By automating data exchange between instruments and the LIS, laboratories achieve faster workflows, improved accuracy, and better patient outcomes. Whether using ASTM, HL7, or other communication standards, analyzer-LIS connectivity has become a fundamental component of efficient and reliable laboratory services.

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